Clavulanate potassium

C-2647
  • CAS: 61177-45-5
  • Formula: C8H8NO5K
  • MW: 237.3
  • Appearance: White to off-white powder
  • Purity: >98% by HPLC

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*Please inquire the availability for this product. Clavulanic acid is a β-lactam antibiotic produced by several species of Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic, but is a potent inhibitor of β-lactamases. In combination with penicillin and cephalosporins, it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the β-lactamase.

Additional Information

SynonymsClavubactam potassium, BRL 14151
Product #C-2647
CAS #61177-45-5
FormulaC8H8NO5K
MW237.3
AppearanceWhite to off-white powder
Purity>98% by HPLC
SolubilitySoluble in Methanol and Water
Melting Point>175 °C
Storage TempRoom temperature
Therapeutic AreaInfectious Diseases
UseAntibiotic used to treat a wide variety of bacterial infections

Additional Information

MDL NumberMFCD01710901
InChIInChI=1S/C8H9NO5.K/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h1,6-7,10H,2-3H2,(H,12,13);/q;+1/p-1/b4-1-;/t6-,7-;/m1./s1
SMILESC1[C@@H]2N(C1=O)[C@H](/C(=C/CO)/O2)C(=O)[O-].[K+]

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