Clozapine

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Clozapine

C-1045
  • CAS: 5786-21-0
  • Formula: C18H19CIN4
  • MW: 326.83
  • Appearance: Off-White to Light Yellow Solid
  • Purity: 98%

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Antipsychotic with greater affinity for D4 dopamine receptor versus D2 or D3 dopamine receptors.

Additional Information

SynonymsClozaril, Leponex
Product #C-1045
CAS #5786-21-0
Chemical Name8-Chloro-11-(4-methyl-1-piperazinyl)-5Hdibenzo[ b,e]-[1,4]diazepine
FormulaC18H19CIN4
MW326.83
AppearanceOff-White to Light Yellow Solid
Purity98%
SolubilitySoluble in DMSO or Dilute Aqueous Acid.
Storage TempRoom Temp
Therapeutic AreaPsychological Disorders
UseA selective inhibitor for D4-dopamine and several serotonin receptors used in the treatment of schizophrenia

Additional Information

Merck IndexMerck Index: 13.2448.2001
MDL NumberMFCD00153785
ChemACXX1004223-0
InChIInChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
SMILESCN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42

Additional Information

GHS Pictograms
RTECSHP1750000
UN #'SUN 2811
PACKING GROUPIII
HandlingStore in Tightly Sealed Vial

Additional Information

Certificate of Analysis 1C-1045, E1324.pdf
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