Dextran Sulfate Sodium Salt

D-2571
  • CAS: 9011-18-1
  • MW: ~500,000 Da
  • Appearance: White to off-white crystalline powder
  • Purity: >99.0%

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Description

Dextran sulfate is an anionic polymer of sulfated glucose and acts as an accelerant for nucleic acid hybridizations. Dextran sulfate accelerates hybridizations by excluding nucleic acids from the volume of solution containing the polymer, thus increasing the effective probe concentration.

In a model of irritable bowel syndrome (IBD) in mice, oral doses of dextran sulfate have been found to yield inflammation of the colon. The substance can also be used to induce varying models of IBD, including acute, chronic, and relapsing conditions.

For solution format, see product Dextran Sulfate, 50% Solution (D-2603).

 

Applications

• Nucleic acid hybridizations: accelerant for faster probe annealing
• Anti-coagulant properties due to ability to precipitate lipoproteins from plasma solutions
• Ribosomal isolations

 

Specifications

• Free sulfate content: <0.02%
• RNase: not detected
• DNase: not detected

 

Additional Information

SynonymsSodium dextran sulfate
Product #D-2571
CAS #9011-18-1
Chemical Namedextran, hydrogen sulfate, sodium salt
MW~500,000 Da
AppearanceWhite to off-white crystalline powder
Purity>99.0%
SolubilityWater
Storage TempRoom temperature
UseAccelerant for nucleic acid hybridizations

Additional Information

Additional Information

GHS Pictograms
HandlingUse only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.

Additional Information

msds 1D-2571, Dextran Sulfate Sodium Salt, SDS, diamond format.pdf
Certificate of Analysis 1D-2571, H1118D.pdf
Certificate of Analysis 2D-2571, H1118C.pdf
Certificate of Analysis 3D-2571, H1118B.pdf
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