Doxorubicin hydrochloride

D-2539
  • CAS: 25316-40-9
  • Formula: C27H30ClNO11
  • MW: 579.98
  • Purity: 99.47%

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Doxorubicin hydrochloride (adriamycin) is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for human therapeutic use as an antitumor agent for the treatment of a wide range of cancers. Doxorubicin also exhibits anti-HIV and antibacterial activity. The mode of action of doxorubicin is thought to be due to intercalation of DNA and inhibition of nucleic acid synthesis.

 

Additional Information

SynonymsAdriamycin, Hydroxydaunorubicin hydrochloride
Product #D-2539
CAS #25316-40-9
FormulaC27H30ClNO11
MW579.98
Purity99.47%
SolubilitySoluble in water (partly), and alcohols
Storage Temp4°C
Therapeutic AreaOncological disorders
UseDoxorubicin is commonly used to treat some leukemias and Hodgkin's lymphoma

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MDL NumberMFCD00077757
SMILESCOC1=C2C(C(C(C(O)=C(C[C@](C(CO)=O)(O)C[C@@H]3O[C@@]4([H])C[C@H](N)[C@H](O)[C@H](C)O4)C3=C5O)=C5C2=O)=O)=CC=C1.[H]Cl

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