2-8°C
Consists of immobilized polymyxin B on 6B-CL. The polymyxins are a family of antibiotics that contain a cationic cyclopeptide with a fatty acid chain. Polymyxin B neutralizes the biological activity of endotoxins by binding to the lipid A portion of bacterial lipopolysaccharide. The immobilized polymixin B gel is a stable affinity matrix that resists leaching of ligand into the valuable preparation. Affisorbent™ Endotoxin Removing Gel can also be used to remove endotoxins from nucleic acid (DNA) samples.Polymyxin B- 6B-CL is used in protein chromatography, affinity chromatography and specialty resins. Polymyxin B- 6B-CL has been used to study periodontitis and endodontic infections as well as obesity and type 2 diabetes. Polymyxin B- 6B-CL is also used for the removal of endotoxin levels in protein solutions, cell culture media, ascites.
Technical Specifications:
- Ligand: Polymyxin B
- Matrix: 6B-CL (crosslinked agarose beads, 6%)
- Particle size range: 52 – 165 µm
- Matrix activation: Cyanogen bromide
- Attachment: Amino group
- Binding capacity: 200 – 500 µg LPS from E. coli serotype 0128:B12
- pH stability: 3 – 10
- Supplied as slurry in 50% glycerol containing 0.02% sodium azide
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
