Galardin; Ilomastat
142880-36-2
388.5
C20H28N4O4
DMF, DMSO, DMSO:PBS (pH 7.2) (1:1), Ethanol
-20°C
GM 6001 is a potent, cell-permeable, broad-spectrum hydroxamic acid inhibitor of matrix metalloproteinases (MMPs); (Ki = 400 pM for MMP-1; Ki = 500 pM for MMP-2; Ki = 27 nM for MMP-3; Ki = 100 pM for MMP-8; and Ki = 200 pM for MMP-9).
GM 6001 prevents the release of TNF-a in vivo and in vitro and abrogates endotoxin-induced lethality in mice.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
