Ionomycin, Free Acid

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Ionomycin, Free Acid

I-1014
  • CAS: 56092-81-0
  • Formula: C41H72O9
  • MW: 709
  • Appearance: Waxy colorless to yellow material
  • Purity: 99.57%

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Ionomycin, free acid, is a highly specific ionophore useful in studying Ca2+ transportation. FromStreptomyces conglobatus. Highly specific ionophore useful in studying Ca2+ transportation.The Mitochondrial Permeability Transition Regulates Cytochrome c Release for Apoptosis during Endoplasmic Reticulum Stress by Remodeling the Cristae Junction.HIV-1-Specific Interleukin-21+ CD4+ T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8+ T Cell Function.Frequent and Strong Antibody-Mediated Natural Killer Cell Activation in Response to HIV-1 Env in Individuals with Chronic HIV-1 Infection.LIME acts as a transmembrane adapter mediating BCR-dependent B-cell activation.Immune-driven recombination and loss of control after HIV superinfection.

Additional Information

Product #I-1014
CAS #56092-81-0
Chemical Name(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-TRIHYDROXY-22-((2S,2'R,5S,5'S)-5'-((R)-1-HYDROXYETHYL)-2,5'-DIMETHYLOCTAHYDRO-[2,2'-BIFURAN]-5-YL)-4,6,8,12,14,18,20-HEPTAMETHYL-9-OXODOCOSA-10,16-DIENOIC ACID
FormulaC41H72O9
MW709
AppearanceWaxy colorless to yellow material
Purity99.57%
SolubilityDMSO/DCM/CH3OH: clear colorless solution at 10 mg/ml
Storage TempStore at room temperature. Protect from light.
UseA potent and selective calcium ionophore

Additional Information

MDL NumberMFCD06798385
ChemACXX1098403-1
InChIInChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1
SMILESC[C@H](CCC(=O)O)C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)O

Additional Information

GHS Pictograms
RTECSNO0600000
HandlingWarning.Toxic. May be Carcinogenic. May be Teratogenic. Protect from Light

Additional Information

msds 1I-1014, Ionomycin, SDS, diamond format.pdf
Certificate of Analysis 1I-1014, H1300A.pdf
Certificate of Analysis 2I-1014, H1300.pdf
Certificate of Analysis 3I-1014, G1054A.pdf
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