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Kainic Acid (Natural)

K-1013
  • CAS: 487-79-6
  • Formula: C10 H15 N O4
  • MW: 213.23
  • Appearance: White to Off white powder
  • Purity: >99% by HPLC

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Kainic acid is a natural marine product originally isolated from the red marine alga D. Simplex. It is a potent central nervous system stimulant, acting through specific kainate receptors and has been developed as the prototype neuroexcitatory amino acid for the induction of seizures in experimental animals, at a typical dose of 10-30 mg/kg in mice. Kainic acid is utilised in primary neuronal cell cultures and acute brain slice preparations to study the physiological effect of excitotoxicity and assess the neuroprotective capabilities of potential therapeutics.

Additional Information

Synonyms(-)-a-Kainic Acid
Product #K-1013
CAS #487-79-6
Chemical Name(2S,3S,4S)-3-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
FormulaC10 H15 N O4
MW213.23
AppearanceWhite to Off white powder
Purity>99% by HPLC
SolubilitySoluble in water (10 mg/mL)
Storage TempStore desiccated at Room Temp.
Therapeutic AreaNeurological Disorders
UseAn excitatory and excitotoxic glutamate-mimic kainate receptor agonist used in epilepsy

Additional Information

MDL NumberMFCD00077806
ChemACXX1063761-9
InChIInChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
SMILESCC(=C)[C@H]1CN[C@@H]([C@H]1CC(=O)O)C(=O)O

Additional Information

GHS Pictograms
RTECSUX9665250
HandlingStore in Tightly Sealed Vial Protect from Moisture. New lot for 2012 has updated storage specification, Room Temperature.

Additional Information

Certificate of Analysis 1K-1013, J1018.pdf
Certificate of Analysis 2K-1013, H1230A.pdf
Certificate of Analysis 3K-1013, H1230.pdf
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