Kainic Acid (synthetic)

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Kainic Acid (synthetic) K-1012
  • Formula: C10H15NO4
  • MW: 213.2
  • Appearance: White to off white crystalline powder
  • Purity: >98%

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Kainic acid is a natural marine product originally isolated from the red marine alga D. Simplex. It is a potent central nervous system stimulant, acting through specific kainate receptors and has been developed as the prototype neuroexcitatory amino acid for the induction of seizures in experimental animals, at a typical dose of 10-30 mg/kg in mice. Kainic acid is utilized in primary neuronal cell cultures and acute brain slice preparations to study the physiological effect of excitotoxicity and assess the neuroprotective capabilities of potential therapeutics.

Additional Information

Synonyms(-)-a-Kainic Acid
Product #K-1012
Chemical Name(2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine)
FormulaC10H15NO4
MW213.2
AppearanceWhite to off white crystalline powder
Purity>98%
SolubilitySoluble in water at 10 mg/mL
Melting Point251°C
Storage TempStore desiccated at room temperature. Protect from light.
Therapeutic AreaNeurological Disorders
UseKainic acid is a potent central nervous system excitant that is used in epilepsy

Additional Information

Merck IndexMerck Index: 13.5294.2001
MDL NumberMFCD00077806
ChemACXX1063761-9
InChIInChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
SMILESCC(=C)[C@H]1CN[C@@H]([C@H]1CC(=O)O)C(=O)O

Additional Information

HandlingStore in Tightly Sealed Vial

Additional Information

Certificate of Analysis 1K-1012, H1433.pdf
Certificate of Analysis 2K-1012, H1402.pdf
Certificate of Analysis 3K-1012, H1344.pdf
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