Kanamycin is an aminoglycosidic antibiotic that inhibits growth of gram-positive, gram-negative bacteria and mycoplasmas in cell culture. Kanamycin or kanamycin A is a major component of the antibiotic complex produced by certain strains of Streptomyces kanamyceticus. Kanamycin is supplied in two forms, a crystalline monosulfate monohydrate and a salt with a higher sulfate content. Kanamycin sulfate, which is sometimes referred to as “kanamycin bisulfate,” is obtained by adding sulfuric acid to a solution of the monosulfate and drying using a suitable procedure. Kanamycin sulfate binds to 30S ribosomes causing inhibition of bacterial protein synthesis.
Laboratory Use - resistance marker to grow plasmids of interest in competent bacterial cells.
Therapeutic Use - a second-line anti-tuberculosis drug.
|Synonyms||Kanamycin, Kanamycin A, Kanamycin Bisulfate, Kanamycin sulfate salt|
|Appearance||White or almost white crystalline powder|
|Solubility||Soluble in water|
|Storage Temp||Room temperature|
|Therapeutic Area||Bacterial infections|
|Use||Antibacterial and anti-tuberculosis agent|
|msds 1||K-1022, Kanamycin sulfate, SDS, diamond format.pdf|
|Certificate of Analysis 1||K-1022, H1116A.pdf|
|Certificate of Analysis 2||K-1022, H1116.pdf|
|Certificate of Analysis 3||K-1022, F1061D.pdf|
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