Beta lactamase, Improve bacterial infection test

More Views

Beta lactamase, Improve bacterial infection test L-1163
Buy 2 Get 1 Free! Use Promo code B2G1 at Check out!
  • CAS: 9073-60-3
  • Appearance: Freeze dried powder

2

1

0

-

Hazardous
Add to Cart Bulk Inquiry

Beta-lactamases are enzymes produced by bacteria (Also known as Penicillinase) that provide resistance to β-lactam antibiotics such as penicillins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. Beta-lactamase provides antibiotic resistance by breaking the antibiotics structure.

These antibiotics all have a common element in their molecular structure: a four-atom ring known as a β-lactam. Through hydrolysis, the lactamase enzyme breaks the β-lactam ring open, deactivating the molecule's antibacterial properties.Beta-lactam antibiotics are typically used to treat a broad spectrum of Gram-positive and Gram-negative bacteria. Beta-lactamases produced by Gram-negative organisms are usually secreted, especially when antibiotics are present in the environment.

APPLICATIONS

1. Testing sterility of blood cultures.

Blood cultures are routinely prepared in order to test for bacterial infection. False negative results might be obtained where the blood sample contains antibiotics. Incorporation of β-Lactamase in the culture medium will overcome this problem when cephalosporins/penicillins are present.

2. Testing for contamination of drugs by antibiotics.

US Code of Federal regulations states that “If a reasonable possibility exists that a non-penicillin drug product has been exposed to cross-contamination with penicillin, the non-penicillin drug product shall be tested for the presence of penicillin” (21 CFR 211.176, Penicillin Contamination, FDA, BY-Lines No. 8 November 1977).

3. Environmental monitoring of antibiotic manufacturing area.

4. Sterility testing of Bulk antibiotics as described by US Pharmcopeia (USP) Chapter 71 and EP Section 2.6.

 

Additional Information

SynonymsEC Number: EC 3.5.2.6
Product #L-1163
CAS #9073-60-3
Chemical Namepenicillin amido-β-lactam hydrolase
AppearanceFreeze dried powder
SolubilitySoluble in Water.
PreparationVialed products are stabled as supplied > 2yrs.
Storage Temp+4°C

Additional Information

Additional Information

GHS Pictograms

Additional Information

msds 1L-1163, SDS.pdf
Certificate of Analysis 1L-1163, J1172.pdf
Certificate of Analysis 2L-1163, H1198.pdf
Certificate of Analysis 3L-1163, G1057.pdf
Close pop-up box

Personal Information

* Required Fields

Additional Information

Additional Information

No Items Found

Newsletter

Got Questions? We have Answers!

Our team of experts are standing by to help you in every possible way.

Real People, Real Time, Rapid Response

Chip Lindgren

Founder/CEO

Ken Smith

Operations

Kyle Anderson

Procurement & Business Development

Amrutha Karuturi

Website and Marketing

Lucrezia Capano

Customer Service

BULK ENQUIRY FORM

* Required Fields

*
*
*
*
*
*Bulk OEM Multiple Catalog Custom Other
Prod#CAS#*PRODUCT NAMEGrade*Size*QtyTime Frame

Custom magento captcha module from Outsource Online