MnTMPyP Pentachloride

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MnTMPyP Pentachloride

M-1020
  • Formula: C44H36MnN8CI5
  • MW: 909.1
  • Appearance: Crystalline Solid
  • Purity: 98%

Hazardous
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MnTMPyP pentachloride is a cell-permeable, manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic. It has displayed the ability to catalyze the dismutation of O2, even in the presence of excess EDTA and it also displays a protective effect against H2O2-mediated damage. Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism. Sulfonylurea Receptor-Dependent and -Independent Pathways Mediate Vasodilation Induced by ATP-sensitive K+ channel openers. Redox regulation of endogenous substrate oxidation by cardiac mitochondria.

 

Additional Information

SynonymsManganese (III) tetrakis(1-methyl-4-pyridyl)porphyrin, MnTMPyP 5Cl
Product #M-1020
Chemical NameManganese (III) tetrakis(1-methyl-4-pyridyl)porphyrin
FormulaC44H36MnN8CI5
MW909.1
AppearanceCrystalline Solid
Purity98%
SolubilitySoluble in Water
Storage Temp+4°C
UseMnTBAP chloride is a cell permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger

Additional Information

InChIInChI=1S/C44H36N8.Mn/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31;/h5-28H,1-4H3;/q+2;+3
SMILESC[N+]1=CC=C(C=C1)C2=C3C=CC(=C(C4=NC(=C(C5=CC=C([N-]5)C(=C6C=CC2=N6)C7=CC=[N+](C=C7)C)C8=CC=[N+](C=C8)C)C=C4)C9=CC=[N+](C=C9)C)[N-]3.[Mn+3]

Additional Information

HandlingStore in Tightly Sealed Vial Protect from Moisture.

Additional Information

Certificate of Analysis 1M-1020_M-1020,_MnTMPyP,_A9653.pdf
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