Nargenicin A1

N-2409
  • CAS: 70695-02-2
  • Formula: C28H37NO8
  • MW: 515.6
  • Appearance: Off-white powder
  • Purity: ≥98% (HPLC)

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Nargenicin A1 isolated from Actinomyces sp. Gö301 is a 28-membered polyketide macrolide, with antibacterial activity against methicillin-resistant Staphylococcus aureus.

Nargenicin A1 is an antibiotic against Gram-positive bacteria, particularly Staphylococcus and Clostridia. It is more effective against multi-resistan strains(MRSA) than erythromycin and vancomycin. But it shows low cytotoxicity compared to erythromycin and spiramycin. Nargenicin A1 inhibits cell proliferation and induces HL-60 cell differentiation in combination with 1,25-Dihydroxyvitamin-D3 and ATRA.

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SynonymsCP-47,444, CS682
Product #N-2409
CAS #70695-02-2
FormulaC28H37NO8
MW515.6
AppearanceOff-white powder
Purity≥98% (HPLC)
SolubilitySoluble in DMSO or methanol
Storage Temp-20°C

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