Netropsin; Congocidin; Sinanomycin
18133-22-7
503.39
C18H26N10O3 • 2HCl
Methanol
-20°C
Netropsin dihydrochloride isolated from Streptomyces netropsis,
Netropsin dihydrochloride is a DNA minor groove binding ligand that shows potential antibiotic and antiviral properties. It displays a strong affinity for the AT-rich region in double-stranded DNA, acting as a binding ligand to nucleic acid.
Netropsin has been reported to bind to double-stranded DNA at specific base sequences and can block DNA helicase, topoisomerase, and endonuclease. It has also been reported to interfere with transcription factor binding. It binds to double-stranded DNA in a non-intercalative manner when used as an antibiotic.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.