Nigericin, Sodium Salt,Polyether ionophore

N-1103
  • CAS: 28643-80-3
  • Formula: C40H67O11Na
  • MW: 747
  • Appearance: White to off-white Powder
  • Purity: 98%

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Polyether ionophore. Stimulates ATPase activity in mitochondria.

Additional Information

SynonymsNigericin Na; Anitbiotic K 178; Polyetherin A; Azalomycin M; Helixin C
Product #N-1103
CAS #28643-80-3
Chemical NameSODIUM (2S)-2-[(3R)-6-[[(2S,4R,5R,9R,10R)-2-[(5S)-5-[(3R)-5-[(3S,5R,6R)-6-HYDROXY-6-(HYDROXYMETHYL)-3,5-DIMETHYLOXAN-2-YL]-3-METHYLOXOLAN-2-YL]-5-METHYLOXOLAN-2-YL]-9-METHOXY-2,4,10-TRIMETHYL-1,6-DIOXASPIRO[4.5]DECAN-7-YL]METHYL]-3-METHYLOXAN-2-YL]PROPANO
FormulaC40H67O11Na
MW747
AppearanceWhite to off-white Powder
Purity98%
SolubilitySoluble in DMSO
Melting Point183.1-187.2 °C
Storage Temp-20°C
UseA polyether antibioitc K+ and Na+ ionophore

Additional Information

MDL NumberMFCD00036825
ChemACXX4634488-5
InChIInChI=1S/C40H68O11.Na/c1-21-11-12-28(46-33(21)26(6)36(42)43)17-29-18-30(45-10)27(7)40(48-29)25(5)19-38(9,51-40)32-13-14-37(8,49-32)35-23(3)16-31(47-35)34-22(2)15-24(4)39(44,20-41)50-34;/h21-35,41,44H,11-20H2,1-10H3,(H,42,43);/q;+1/p-1/t21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35+,37-,38-,39-,40+;/m0./s1
SMILESC[C@H]1CC[C@@H](O[C@H]1[C@@H](C)C(=O)[O-])C[C@@H]2C[C@H]([C@H]([C@@]3(O2)[C@@H](C[C@@](O3)(C)[C@H]4CC[C@@](O4)(C)[C@H]5[C@H](C[C@@H](O5)[C@@H]6[C@H](C[C@H]([C@@](O6)(CO)O)C)C)C)C)C)OC.[Na+]

Additional Information

GHS Pictograms
RTECSQT6825000
UN #'SUN 3462
PACKING GROUPIII
HandlingStore in Tightly Sealed Vial

Additional Information

msds 1N-1103, Nigericin, SDS, diamond format.pdf
Certificate of Analysis 1N-1103, G1009A.pdf
Certificate of Analysis 2N-1103, G1009, r01.pdf
Certificate of Analysis 3N-1103, E1219.pdf
E-Brochure Fermentation
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