Nystatin

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Nystatin

N-2683
  • CAS: 1400-61-9
  • Formula: C47H75NO17
  • MW: 926.1 Da
  • Appearance: Yellow to off-white powder

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Description

Polyene antifungal antibiotic produced by Streptomyces noursei.

Nystatin is a polyene antifungal, antibiotic complex containing three biologically active components: A1, A2, and A3. It increases the permeability of the cell membrane of sensitive fungi by binding to sterols. It is a growth promoter.

 

Specifications

EC Number: 215-749-0

Potency (Assay): ≥ 4400 U/mg

*Residual Solvent (n-butanol): ≤ 1000 ppm

*Residual Solvent (Methanol): ≤ 3000 ppm

*Residual Solvent (Acetone): ≤ 5000 ppm

*Solvents may be present in this product. All comply with the limits prescribed in the current USP.

Additional Information

SynonymsFungicidin, Mycostatin, Nilstat, Nystatin A1, Nystatin A2, Nystatin A3, Nystatin G, Stamicin, Stamycin
Product #N-2683
CAS #1400-61-9
Chemical Name(4E,6E,8E,10E,14E,16E,18S,19R,20R,21S,35S)-3-[(2S,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carboxylic acid
FormulaC47H75NO17
MW926.1 Da
AppearanceYellow to off-white powder
SolubilityDMSO
Storage Temp2-8°C

Additional Information

MDL NumberMFCD25541651
ChemACXX1004338-6
PubChecm ID6433272
InChIInChI=1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31?,32?,33?,34?,35?,36?,37?,38?,40?,41-,42+,43+,44-,46+,47+/m0/s1
SMILESC[C@H]1/C=C/C=C/CC/C=C/C=C/C=C/C=C/C(CC2C(C(C[C@](O2)(CC(C(CCC(CC(CC(CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O

Additional Information

Additional Information

Certificate of Analysis 1N-2683, J1156.pdf
Certificate of Analysis 2N-2683, H1028A.pdf
Certificate of Analysis 3N-2683, H1028.pdf
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