Okadaic acid. Potassium Salt, Prorocentrum concavum | CAS 155751-72-7

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Okadaic acid Potassium Salt, Prorocentrum concavum

O-1028
  • CAS: 155751-72-7
  • Formula: C44H67O13.K
  • MW: 843.09
  • Appearance: White or clear solid (faint film) Barely visible.
  • Purity: >98%

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Okadaic acid was first isolated from the marine sponges Halichondria okadai and Halichondria melanodocia. Okadaic acid is a protein phosphatase PP-1 and PP-2A inhibitor and has been used extensively as a probe to identify cellular processes that are regulated by phosphorylation and dephosphorylation and for the identification of phosphatases. Also used as a tumor promoter. This salt form provides increased stability in solution. See our other Okadaic Acid's O-1024, O1026, O-1030.

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Additional Information

SynonymsHalochondrine A . potassium salt; 9,10-Deepithio-9,10-didehydroacanthifolicin sodium salt (high purity)
Product #O-1028
CAS #155751-72-7
Chemical Name9,10-Deepithio-9,10-didehydroacanthifolicin . potassium salt
FormulaC44H67O13.K
MW843.09
AppearanceWhite or clear solid (faint film) Barely visible.
Purity>98%
SolubilitySoluble in DMSO, ethanol or methanol.
Melting Point164-166°C
Storage TempStore desiccated at -20°C. Packaged under argon gas.
Therapeutic AreaOncological Disorders
UseNon-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor.Apoptosis inhibitor. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells

Additional Information

Merck IndexMerck Index: 13.6891.2001
MDL NumberMFCD00213389
ChemACXX1094109-2
InChIInChI=1S/C44H68O13.K/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);/q;+1/p-1/b10-9+;/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37+,38+,39-,41-,42+,43-,44-;/m1./s1
SMILESC[C@@H]1CC[C@]2(CCCCO2)O[C@@H]1[C@@H](C)C[C@@H]([C@@H]3C(=C)[C@H]([C@H]4[C@H](O3)CC[C@]5(O4)CC[C@@H](O5)/C=C/[C@@H](C)[C@@H]6CC(=C[C@@]7(O6)[C@@H](CC[C@H](O7)C[C@](C)(C(=O)[O-])O)O)C)O)O.[K+]

Additional Information

GHS Pictograms
UN #'SUN 2811
PACKING GROUPII
HandlingWarning.Toxic. May be Carcinogenic. May be Teratogenic. Wear gloves/ mask when handling product. Protect from Light

Additional Information

Certificate of Analysis 1O-1028, H1122D.pdf
Certificate of Analysis 2O-1028, H1122C.pdf
Certificate of Analysis 3O-1028, H1122B.pdf
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