P32/98, DPP IV Inhibitor | CAS 136259-20-6 | AG Scientific, Inc.

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P32/98, DPP IV Inhibitor (CD26)

  • CAS: 136259-20-6
  • Formula: C9H18N2OS • 0.5C4H404
  • MW: 260.4 Da
  • Appearance: White powder
  • Purity: >98% (TLC)




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P32/98 is a cell-permeable, potent and selective inhibitor of dipeptidyl peptidase IV (DPPIV) (Ki=130nM). May be used in cell culture (1-10 mM) or in vivo (10 mg/Kg orally).  It has been hypothesized that chronic DPPIV inhibitor treatment of diabetic animals, improves glucose tolerance, enhances β-cell glucose responsiveness, replication, and turnover, and results in sustained improvements in β-cell function.

As previously stated, DPP IV inhibitors are a new class of anti-diabetic drugs. However, DPP IV metabolizes to at least 24 endogenous substrates, the pharmacological consequences of inhibiting the metabolism of most of these substrates is unknown. Research studies have shown that DPP IV is expressed in the renal microcirculation and inhibition of this ectoenzyme causes arterial PYY1–36 to more effectively enhance angiotensin II-induced renal vasoconstriction in genetically susceptible kidneys.



P32/98 is a specific, competitive transition state substrate analog inhibitor of dipeptidyl peptidase IV (DPP-IV, DPIV, CD26, CD-26). Useful in diabetes research, as well as, protein preservation studies & transport.


Additional Information

SynonymsDPPIV, DPP-IV, dipeptidyl peptidase IV, CD26, CD-26.
Product #P-1685
CAS #136259-20-6
Chemical Name(2S, 3S)-2-Amino-3 –methyl-1-(thiazolidin-3-yl)pentan-1-one hemi-fumarate
FormulaC9H18N2OS • 0.5C4H404
MW260.4 Da
AppearanceWhite powder
Purity>98% (TLC)
SolubilityMay be dissolved in H2O (20 mg/ml) or DMSO (25mg/ml).
Storage TempStore desiccated at -20°C
Therapeutic AreaImmuno therapy
UseUseful in diabetes research, as well as, protein preservation studies & transport.

Additional Information

Additional Information

Additional Information

msds 1P-1685, P32-98, SDS, diamond format.pdf
Certificate of Analysis 1P-1685, J1225A.pdf
Certificate of Analysis 2P-1685, J1225 (BD).pdf
Certificate of Analysis 3P-1685, J1160A.pdf
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