Phosphatase Inhibitor Cocktail I | Inhibitors | AG Scientific

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Phosphatase Inhibitor Cocktail I

P-1517
  • Appearance: Clear colorless liquid in 1ml DMSO

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A specially formulated cocktail of three phosphatase inhibitors that will inhibit alkaline phosphatases and serine/threonine protein phosphatases such as PP1 and PP2A. Recommended for use with tissue and cell extracts, including extracts containing detergents. A specially formulated cocktail of three phosphatase inhibitors that will inhibit alkaline phosphatases and serine/threonine protein phosphatases such as PP1 and PP2A. Each vial contains 2.5 mM (-)-p-bromotetramisole oxalate, 500uM cantharidin and 500 nM microcystin-LR

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Product #P-1517
Chemical NamePHOSPHATASE INHIBITOR COCKTAIL I
AppearanceClear colorless liquid in 1ml DMSO
PreparationRecommended usage is 100-fold dilution
Storage Temp-20°C

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MDL NumberMFCD01635520
ChemACXX1224363-9

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msds 1P-1517, Phosphatase Inhibitor Cocktail I, SDS, diamond format.pdf
Certificate of Analysis 1P-1517, J1195.pdf
Certificate of Analysis 2P-1517, J1180.pdf
Certificate of Analysis 3P-1517, J1128.pdf
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CitationsGriffin, Amanda J., et al. "Successful protection against tularemia in C57BL/6 mice is correlated with expansion of Francisella tularensis-specific effector T cells." Clinical and Vaccine Immunology 22.1 (2015): 119-128.
Crane, Deborah D., et al. "B1a cells enhance susceptibility to infection with virulent Francisella tularensis via modulation of NK/NKT cell responses." The Journal of Immunology (2013): 1202697.
Park, Jong-Chan, et al. "Chemically treated plasma Aβ is a potential blood-based biomarker for screening cerebral amyloid deposition." Alzheimer's research & therapy 9.1 (2017): 20.
Park, Jong-Chan, et al. "Annexin A1 restores Ab1-42-induced blood-brain barrier disruption through the inhibition of RhoA-ROCK signaling pathway." Aging Cell 16.1 (2017): 149-161.
Rhee, Ki-Jong, et al. "Extract of Ginkgo Biloba ameliorates streptozotocin-induced type 1 diabetes mellitus and high-fat diet-induced type 2 diabetes mellitus in mice." International journal of medical sciences 12.12 (2015): 987.
Kim, Chaeyoung, et al. "HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons." PLoS One 7.8 (2012): e42983.
Song, Hyundong, et al. "Inhibition of glutaminyl cyclase ameliorates amyloid pathology in an animal model of Alzheimer's disease via the modulation of γ-secretase activity." Journal of Alzheimer's Disease 43.3 (2015): 797-807.
Park, R., et al. "Ab1-42 reduces P-glycoprotein in the blood-brain barrier through RAGE-NF-kB signaling." Cell death & disease 5.6 (2014): e1299.
Mook, Inhee, et al. "Method for clinically and pathologically monitoring alzheimer's disease through concentration of amyloidbeta in plasma." U.S. Patent Application No. 15/570,186.

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