(R,S)-Lenalidomide

L-2170
  • CAS: 191732-72-6
  • Formula: C13H13N3O3
  • MW: 259.26
  • Appearance: White to off-white Solid
  • Purity: 98% by HPLC

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Cell-permeable. An analog of thalidomide that was originally found based on its ability to effectively inhibit tumor necrosis factor production. Lenalidomide is 50,000 times more potent than thalidomide in inhibiting Tumor Necrosis Factor (TNF). Displays potent anti-tumor and anti-inflammatory effects as well as modulates and potentiates host immune responses against multiple myeloma.

Additional Information

Synonyms(R,S)-3-(4-amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione
Product #L-2170
CAS #191732-72-6
Chemical Name(R,S)-3-(4-amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione
FormulaC13H13N3O3
MW259.26
AppearanceWhite to off-white Solid
Purity98% by HPLC
SolubilityDMSO (~100 mg/ml)
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseLenalidomide is a thalidomide analog known to inhibit TNF-α secretion and possess immunomodulatory properties

Additional Information

MDL NumberMFCD07772307
ChemACXX1556398-5
InChIInChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
SMILESc1cc2c(c(c1)N)CN(C2=O)C3CCC(=O)NC3=O

Additional Information

GHS Pictograms
RTECSTM7342160
HandlingProtect from air and light

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