(R)-Semivioxanthin isolated from Penicillium citreo-viride is a mycotoxin showing antibacterial(gram-positive) and antifungal activity.
(R)-Semivioxanthin is immunoregulator by degradation of IκB(Inhibitor of NF-κB) and regulation of the TNF-α(tumor necrosis factor-α) and MAPK(mitogen-activated protein kinase) signaling pathways.
Total synthesis of (R)- and (S)-semi-vioxanthin, D. Drochner et al, J. Org. Chem, 2001 (2001)
Semi-vioxanthin isolated from marine-derived fungus regulates tumor necrosis factor-α, cluster of differentiation(CD) 80, CD86, and major histocompatibility complex class II expression in RAW264.7 cells via nuclear factor-κB and mitogen-activated, X.Y.Yang, et al., Biol. Pharm., Bull, 31 (2008)
|Appearance||Pale yellow to green solid|
|Solubility||Soluble in chloroform, tetrahydrofuran or DMSO; poorly soluble in water|
|Storage Temp||+4°C for short term storage|
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