FK228; FR901228; NSC 630176
128517-07-7
540.7
C24H36N4O6S2
DMF, DMSO, Ethanol
-20°C
Romidepsin is a potent and selective inhibitor of class I histone deacetylases (HDACs), IC50 = 36, 47, 510 and 14,000 nM for HDAC1, 2, 4 and HDAC6, respectively. Induces apoptosis in a variety of cell lines and displays antitumor activity in mouse models. Romidepsin was recently approved for clinical use in T-cell lymphoma.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
