Roxithromycin

R-2611
  • CAS: 80214-83-1
  • Formula: C41H76N2O15
  • MW: 837.1
  • Appearance: White solid
  • Purity: >98% by HPLC

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*Please inquire the availability for this product. Roxithromycin was one of the new generation erythromycins introduced in the 1980s. Improved acid stability was achieved by converting the 9-keto group to the more stable oxime and alkylation of the oxime to provide the methoxyethoxymethyl ether oxime. In vivo, roxithromycin exhibits higher tissue levels and a longer half-life while being slightly less potent than erythromycin in vitro.

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SynonymsErythromycin 9-(-O-[2-methoxyethoxy]methyloxime)
Product #R-2611
CAS #80214-83-1
FormulaC41H76N2O15
MW837.1
AppearanceWhite solid
Purity>98% by HPLC
SolubilitySoluble in HCl and NaOH
Melting Point116-122 °C
Storage Temp4°C
Therapeutic AreaInfectious Diseases
UseRoxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections

Additional Information

MDL NumberMFCD00214389
InChIInChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31+/t22-,23-,24+,25+,26-,27+,28+,29-,30+,32-,33+,34-,35+,36-,38+,39-,40-,41-/m1/s1
SMILESCC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O

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