Sarcophine

S-2418
  • CAS: 55038-27-2
  • Formula: C20H28O3
  • MW: 316.4
  • Appearance: White to off-white solid
  • Purity: ≥97% (HPLC)

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Sarcophine is a cembranoid marine natural product that is reposted to possess cancer chemopreventive properties.

It was found to be an effective inhibitor of JB6 cell transformation. Sarcophine is acetylcholine esterase and ATPase inhibitor.

From the soft bodied coral Sarcophytum glaucum a crystalline compound-sarcophine, which is believed to be one of the repellents protecting the coral against predators, was isolated. 

The recent study showed sarcophine-diol's possible use in prevention of skin cancer to consider its potential as a tool in therapies to actually treat skin cancer. Sarcophine-diol induced apoptosis, or programmed cell death in cancer cells in this study. But sarcophine-diol didn't induce what scientists call necrosis, or the premature death of healthy cells. The experiment also looke at whether sarcophine-diol treatments could increase what is called DNA fragmentation, considered a biochemical hallmark of apoptosis.

Additional Information

SynonymsNSC250434
Product #S-2418
CAS #55038-27-2
FormulaC20H28O3
MW316.4
AppearanceWhite to off-white solid
Purity≥97% (HPLC)
SolubilitySoluble in methanol or dichloromethane
Storage Temp-20°C

Additional Information

Additional Information

Additional Information

msds 1S-2418, Sarcophine, SDS, diamond format.pdf
Certificate of Analysis 1S-2418, F1142.pdf
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