Tamoxifen citrate

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Tamoxifen citrate T-2451
  • CAS: 54965-24-1
  • Formula: C26H29NO C6H8O7
  • MW: 563.64
  • Appearance: White Solid
  • Purity: 99%

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A potent synthetic anti-estrogenic agent. A reversible inhibitor of protein kinase C (IC= 10 mM). Induces apoptosis in human malignant glioma cell lines and inhibits prostate cancer cell growth by induction of p21 protein.

Additional Information

Synonyms(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
Product #T-2451
CAS #54965-24-1
Chemical Name(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
FormulaC26H29NO C6H8O7
MW563.64
AppearanceWhite Solid
Purity99%
SolubilityEtOH or MeOH
Melting Point140-142 °C
Boiling Point482.3 °C at 760 mmHg
Storage Temp-20°C
Therapeutic AreaOncological Disorders
UseAn antiestrogen with potent anti-cancer and PKC inhibitory activities

Additional Information

MDL NumberMFCD00058321
ChemACXX1009164-6
InChIInChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;
SMILESCC/C(=C(c1ccccc1)/c2ccc(cc2)OCCN(C)C)/c3ccccc3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Additional Information

RTECSKH2387000
UN #'SUN 3077
PACKING GROUPIII
HandlingProtect from moisture

Additional Information

Certificate of Analysis 1T-2451, E1273.pdf

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