TGR5 Receptor Agonist

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TGR5 Receptor Agonist

T-2457
  • Formula: C18H14Cl2N2O2
  • MW: 361.22
  • Appearance: Crystalline Solid
  • Purity: 98% by HPLC

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Cell-permeable, small molecule agonist of TGR5 G-protein coupled receptor. This agonist has shown to increase glucagon like peptide-1 (GLP-1) secretion from primary intestinal cells.

Additional Information

Synonyms3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethylisoxazole-4-carboxamide
Product #T-2457
Chemical Name3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethylisoxazole-4-carboxamide
FormulaC18H14Cl2N2O2
MW361.22
AppearanceCrystalline Solid
Purity98% by HPLC
SolubilityDMSO
Storage Temp-20°C

Additional Information

MDL NumberMFCD17169972
InChIInChI=1S/C18H14Cl2N2O2/c1-11-16(17(21-24-11)14-5-3-4-6-15(14)20)18(23)22(2)13-9-7-12(19)8-10-13/h3-10H,1-2H3
SMILESCc1c(c(no1)c2ccccc2Cl)C(=O)N(C)c3ccc(cc3)Cl

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HandlingProtect from air and light

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