Virginiamycin complex

  • CAS: 11006-76-1
  • Formula: C28H35N3O7 (for M1), C43H49N7O10 (for S1)
  • MW: 525.6 (for M1); 823.9 (for S1)
  • Appearance: White solid
  • Purity: >99% by HPLC (75% Virginamycin M1, 20% Virginiamycin S1, 5% Other minor analogues)

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*Please inquire the availability for this product. Virginiamycin complex is defined as a mixture of 75% ostreogrycin A (virginiamycin M1) and 25% virginiamycin S1, together with the less abundant S analogues. As the two major components have quite different solubilities, these proportions are not readily achieved or used. The composition of the complex is important as Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

Additional Information

SynonymsCebin V, Eskalin V, Eskamicin, Stafac, Stephylomycin, Mikamycin, Ostreogrycin, Patricin, Pristinamycin, Streptogramin, Vernamycin.
Product #V-2501
CAS #11006-76-1
Chemical NameN-[(6R,9S,10R,13S,15AS,22S,24AS)-22-BENZYL-6-ETHYL-10,23-DIMETHYL-5,8,12,15,17,21,24-HEPTAOXO-13-PHENYLDOCOSAHYDRO-12H-PYRIDO[2,1-F]PYRROLO[2,1-L][1,4,7,10,13,16]OXAPENTAAZACYCLONONADECIN-9-YL]-3-HYDR OXY-2-PYRIDINECARBOXAMIDE - (10R,11R,12Z,17Z,19Z,21S)-
FormulaC28H35N3O7 (for M1), C43H49N7O10 (for S1)
MW525.6 (for M1); 823.9 (for S1)
AppearanceWhite solid
Purity>99% by HPLC (75% Virginamycin M1, 20% Virginiamycin S1, 5% Other minor analogues)
SolubilitySoluble in DMF, DMSO, ethanol (limited), methanol (limited), and water (poor)
Storage Temp-20

Additional Information

MDL NumberMFCD01778146
SMILESCC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N(C(C(=O)N3CCC(=O)C[C@H]3C(=O)N[C@H](C(=O)O[C@ @H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C.C[C@@H] 1/C=C/C(=O)NC/C=C/C(=C/[C@H](CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)O[C@@H]1C(C )C)O)/C

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