IKK Inhibitor II
524-12-9
314.3
C16H10O7
DMF, DMSO, Ethanol
-20°C
Wedelolactone is a cell permeable, selective and irreversible IKKα and β kinase activity inhibitor. NF-κB inhibitor. Blocks phosphorylation and degradation of IκBα. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor. Anti-inflammatory. HIV-1 integrase inhibitor. Anticancer and antiproliferative compound. Modulates androgen receptor (AR) activation. Apoptosis inducer via downregulation of PKCε. DNA topoisomerase IIα inhibitor. G protein-coupled receptor-35 (GPR35) agonist. Inhibits adipogenic differentiation of mesenchymal stem cells (hAMSCs) through ERK pathway. STAT1 protein dephosphorylation inhibitor. Antifibrotic.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.